Even though most of us don’t know who Fatty Arbuckle is, he was a popular comedian during the 1910s and ’20s. He worked alongside Charlie Chaplin and became one of the highest-paid actors in Hollywood. But he flushed this fame and fortune down the toilet after he allegedly murdered Virginia Reppe in 1921 by rupturing her bladder. This caused her to mysteriously become ill and then died four days later. The ordeal was a huge scandal and even though he was acquitted of the charges, his career never revived (via History).